How often is lobular breast cancer Bilateral?
Previous studies have demonstrated the propensity of lobular carcinoma to occur bilaterally. This view is supported by the large number of lobular cancers found in our patients. Thirty-six percent of the patients with bilateral disease had lobular cancer in at least one breast.
Is lobular breast cancer more likely to recur?
This aggressive phenotype is often associated with a poorer prognosis when compared to other ILC variants (19). Weidner et al. (20) reported that patients with pleomorphic ILC were four times more likely to experience recurrence than patients affected by classic variant and Orvieto et al.
How common is bilateral breast cancer?
Objective: Bilateral breast cancer is uncommon (1-2.6% of all patients with breast carcinoma). There are conflicting reports and inadequate data regarding the incidence and survival of such patients.
How often does lobular cancer recur?
Most studies report local recurrence after relatively short follow-up periods, which is usually 5 years. However there is some evidence to suggest that local recurrence may occur late in the course of follow-up.
Is lobular cancer slow growing?
Invasive lobular carcinoma is known for being a slow growing tumor, usually grade I or II. Slow growing, grade I tumors don’t usually respond well to chemotherapy, so hormonal therapy is key for this type of cancer.
Why did I get lobular breast cancer?
It’s not clear what causes invasive lobular carcinoma. Doctors know that invasive lobular carcinoma begins when cells in one or more milk-producing glands of the breast develop mutations in their DNA. The mutations lead to the inability to control cell growth, which results in the cells dividing and growing rapidly.
Does Chemo shrink lobular breast cancer?
Chemotherapy may be recommended after surgery to kill any cells that may remain. Chemotherapy can also be used before surgery to shrink a tumor that is large. For women with larger tumors, chemotherapy before surgery may make it possible to choose lumpectomy over mastectomy.
Can you survive bilateral breast cancer?
The 5- and 10-year relapse-free survival of patients with bilateral invasive disease, regardless of axillary nodal status and tumor size, was 60% and 51%, respectively, for patients with a bilateral presentation and 54% and 38%, respectively, for carcinomas presenting metachronously.
Which type of breast cancer is most bilateral?
The most common histological type was invasive ductal carcinoma. All eight patients with bilateral breast cancer had at least one type of recurrence/metastasis, mostly in the liver, and statistically the pleuropulmonary and liver metastases were the most frequent causes of death.