Your question: How is transitional cell carcinoma treated?

How long do you live with transitional cell carcinoma?

Overall survival and cancer-specific survival

For the entire cohort, there were 986 (51.6%) patients who died and 704 (36.9%) patients who died from primary transitional cell carcinoma of the ureter. The median overall survival (OS) was 46 months, and the 5-year OS rate was 41.8%.

Where does transitional cell carcinoma metastasis?

Transitional cell carcinoma (TCC) of the bladder commonly metastasizes to the pelvic lymph nodes, lungs, liver, bones, adrenals, or brain. Unusual sites include the heart, kidney, spleen, pancreas, and reproductive system.

How common is transitional cell carcinoma?

It is the most common type of bladder cancer and cancer of the ureter, urethra, and urachus. It accounts for 95% of bladder cancer cases. It is the second most common type of kidney cancer, but accounts for only five to 10 percent of all primary renal malignant tumors.

Transitional cell carcinoma
Specialty Oncology

How serious is transitional cell carcinoma?

If it’s high grade, it’s more likely to spread to deeper layers of your bladder, other areas of your body, and your lymph nodes. It’s also likely to come back after treatment. High-grade TCC is the type of bladder cancer that is more likely to be life-threatening.

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Is transitional cell carcinoma fatal?

Transitional cell carcinoma of the renal pelvis, accounting for only 7% of all kidney tumors, and transitional cell cancer of the ureter, accounting for only 1 of every 25 upper urinary tract tumors, are curable in more than 90% of patients if they are superficial and confined to the renal pelvis or ureter.

Does transitional cell carcinoma spread?

While transitional cell carcinoma originates along the ureter, high-grade cases allow it to spread (metastasize) into other organs and areas of the body. The prostate is the most commonly affected organ, as it is connected to the urinary system via ducts.

What is the primary symptom of transitional cell carcinoma?

The symptoms of transitional cell cancer of the kidney are similar to those of other types of kidney cancer. They include blood in the urine and pain in your back, between the lower ribs, and the top of your hip bone. You may also need to pass urine very often or have pain when passing urine.

How aggressive is urothelial carcinoma?

Muscle-invasive urothelial carcinomas are highly aggressive compared to cancers of the upper urinary tract, carrying a five-year disease-specific survival rate of <50% in pT2/pT3 disease, and this survival rate drops below 10% in pT4 cancer.

Can a cancerous ureter be replaced?

Surgery is often recommended to remove ureteral cancer. The extent of your surgery will depend on your situation. For very early-stage ureteral cancer, surgery may involve removing only a portion of the ureter.

What is upper tract transitional cell carcinoma?

Upper urinary tract transitional cell carcinoma (TCC) refers to malignant changes of the transitional epithelial cells lining the urinary tract from the renal calyces to the ureteral orifice.

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