Why is filgrastim given after chemotherapy?
Filgrastim injection products (Granix, Neupogen, Nivestym, Zarxio) are used to decrease the chance of infection in people who have non myeloid cancer (cancer that does not involve the bone marrow) and are receiving chemotherapy medications that may decrease the number of neutrophils (a type of blood cell needed to …
When is Neupogen given after chemo?
Administer the first dose of NEUPOGEN at least 24 hours after cytotoxic chemotherapy and at least 24 hours after bone marrow infusion.
What is the purpose of administering filgrastim?
Filgrastim injection is used to treat neutropenia (low white blood cells) that is caused by cancer medicines. It is a synthetic (man-made) form of a substance that is naturally produced in your body called a colony stimulating factor. Filgrastim helps the bone marrow to make new white blood cells.
Is filgrastim a chemo drug?
This medication is used to prevent infection and neutropenic (low white blood cells) fevers caused by chemotherapy. Filgrastim is a support medication.
What is the injection given after chemo?
CSFs include Neupogen (filgrastim), Neulasta (pegfilgrastim), and Leukine and Prokine (sargramostim). They are usually given as shots 24 hours after a chemotherapy treatment.
Why is Neupogen given 24 hours after chemo?
This medication is usually given at least 24 hours after chemotherapy to stimulate the growth of new, healthy, white blood cells (WBC). Pegfilgrastim is a longer acting form of filgrastim and the manufacturer recommends that it should not be given within 14 days prior to chemotherapy.
How quickly does Neupogen work?
Patients receiving chemotherapy or who have received a bone marrow or stem cell transplant are only required to use NEUPOGEN for short periods of time until the number of infection-fighting neutrophils are restored (usually 1 to 3 weeks). Stem cell donors should receive NEUPOGEN treatment for 4 to 5 days.
How can I increase my white blood cells after chemo?
The only treatment that has been proved to increase the number of white blood cells after chemotherapy is an injectable medicine that stimulates the bone marrow to make white blood cells faster.
Does Filgrastim need to be given at the same time?
Filgrastim is most often given as a subcutaneous injection (SQ, given under the skin), but it can be given directly into a vein (intravenous, IV). It is given once a day, preferably at the same time of day, until the neutrophil count returns to normal.
Does Filgrastim make you tired?
tired feeling, skin rash, nosebleeds, or. injection site reactions (redness, swelling, itching, lumps or bruising).
Can Neupogen be given at home?
skin (subcutaneous injection). Your healthcare provider may decide subcutaneous injections can be given at home by you or your caregiver. If NEUPOGEN is given at home, see the detailed “Instructions for Use” that comes with your NEUPOGEN for information on how to prepare and inject a dose of NEUPOGEN.
How effective is Neupogen?
Neupogen can be very effective for increasing the level of neutrophils in your body to reduce your risk of infection. Many people experience some bone pain and a fever, but this is usually very mild. Fortunately, the medication is needed only as long as you are receiving chemotherapy and can then be discontinued.
Can Neupogen cause leukemia?
G-CSF use has been associated with later development of myelodysplastic syndromes/acute myelogenous leukemia (MDS/AML) in several clinical circumstances.