What is the normal range for AFP tumor marker?
An AFP level between 10 ng/mL to 20 ng/mL is normal for adults. An extremely high level of AFP in your blood—greater than 400 ng/mL—could be a sign of liver tumors. High levels of AFP may mean other cancers, including Hodgkin disease, lymphoma, and renal cell carcinoma (kidney cancer).
What is an abnormal AFP result?
What do the results mean? If your results show higher than normal AFP levels, it may mean your baby has a neural tube defect such as spina bifida, a condition in which the bones of the spine don’t close around the spinal cord, or anencephaly, a condition in which the brain does not develop properly.
What is AFP test for liver?
AFP (Alfa-fetoprotein) Hepatitis C for Patients
AFP is a protein that is present in patients with liver disease. AFP is also a “tumor marker” and may be used to see if a patient has liver cancer. (Liver cancer is also called hepatocellular carcinoma).
Are AFP tumor markers accurate?
Optimal cutoff values that provide the best LR+ were 200 ng/ml for AFP, 40 mAU/ml for DCP, and 15% for AFP-L3. Conclusions Diagnostic accuracy of AFP in small HCC was substantially limited. Surveillance including other tumor markers with optimal cutoff value should be conducted to confirm the efficacy of the policy.
What can raise AFP levels?
Outside of pregnancy and birth, liver damage and certain cancers can increase AFP levels significantly. This test measures the level of AFP in your blood. AFP is produced whenever liver cells are regenerating. With chronic liver diseases, such as hepatitis and cirrhosis, AFP may be chronically elevated.
What can cause high AFP levels?
Tumor markers are substances made by cancer cells or by normal cells in response to cancer in the body. High levels of AFP can be a sign of liver cancer or cancer of the ovaries or testicles, as well as noncancerous liver diseases such as cirrhosis and hepatitis.
What happens if an AFP test is positive?
What does it mean if my AFP PLUS test result is screen positive? A positive AFP PLUS test means that you are in a higher likelihood group for having a baby with a neural tube defect or a chromosome abnormality. However, it does not prove by itself that there is anything wrong with the pregnancy.
How accurate is AFP test?
The test has a false positive rate of 5 percent. This means that 5 percent of the time, the test is positive but the baby does NOT have an open spine.
What does AFP check for?
An alpha-fetoprotein (AFP) blood test checks the level of AFP in a pregnant woman’s blood. AFP is a substance made in the liver of an unborn baby (fetus). The amount of AFP in the blood of a pregnant woman can help see whether the baby may have such problems as spina bifida and anencephaly.
How do I lower my AFP?
Iron reduction therapy significantly reduced the median level of serum AFP from 13 to 7 ng/mL, ALT from 96 to 50 IU/L, gamma-glutamyl transpeptidase (GGT) from 55 to 28 IU/L, and ferritin from 191 to 10 ng/mL ( for each).
Can fatty liver cause elevated AFP?
The presence of hepatic inflammation and/or fibrosis may be the underlying cause of increased serum AFP levels in patients with severe fatty liver. Necrosis or active regeneration may also play a role in these patients.