What is germ cell tumors?

What kind of cancer is germ cell tumors?

What are germ cell tumors? Germ cell tumors are malignant (cancerous) or nonmalignant (benign, noncancerous) tumors that are comprised mostly of germ cells. Germ cells are the cells that develop in the embryo (fetus, or unborn baby) and become the cells that make up the reproductive system in males and females.

Is germ cell tumor cancer?

Ovarian germ cell tumor is a disease in which malignant (cancer) cells form in the germ (egg) cells of the ovary. Germ cell tumors begin in the reproductive cells (egg or sperm) of the body. Ovarian germ cell tumors usually occur in teenage girls or young women and most often affect just one ovary.

What are the two types of germ cell tumors?

There are two types of germ cell tumors that start in the gonads, or reproductive organs: seminomas, which are slower-growing, and nonseminomas, which are faster-growing tumors. These germ cell tumors typically form during puberty.

What is the survival rate of germ cell tumor?

The survival and cure rates also depend on several factors, including the stage of the disease. The cure rate for children with a stage I or stage II germ cell tumor is 90%. The cure rate for a stage III tumor is 87%. The cure rate for a stage IV tumor is 82%.

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Can germ cell tumor be cured?

If there is a residual tumor present after chemotherapy, surgical resection may be recommended, and additional chemotherapy may be needed. The cure rates are approximately 90% for Stage I, 90% for Stage II, 87% for Stage III, and 82% for Stage IV.

Do germ cell tumors grow fast?

This is a germ cell tumor that is most often malignant, but may also be benign. This tumor most often affects the ovaries or testes, and the lower spine. They are often malignant and grow fast.

How aggressive is germ cell cancer?

It’s often an aggressive cancer that spreads quickly to the lymph nodes and other parts of the body. They’re typically treated with surgery and chemotherapy.

What causes germ cell Tumours?

The cause of most germ cell tumors isn’t always known. Doctors do know that some medical conditions can make children more likely to develop them. These include: birth defects that involve the central nervous system, genitals, urinary tract, and spine.

What percentage of germ cell tumors are malignant?

Malignant germ cell tumors of the mediastinum are uncommon, representing only 3 to 10% of tumors originating in the mediastinum. They are much less common than germinal tumors arising in the testes, and account for only 1 to 5% of all germ cell neoplasms.

Do germ cell tumors come back?

How do providers treat benign (noncancerous) ovarian germ cell tumors? Healthcare providers remove benign tumors surgically. Sometimes, they need to remove the ovary (or part of the ovary) when removing the tumor. Benign tumors rarely grow back after providers remove them.

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Are germ cell tumors rare?

Some germ cell tumors occur in other areas of the body, such as the abdomen, brain and chest, though it’s not clear why. Germ cell tumors that occur in places other than the testicles and ovaries (extragonadal germ cell tumors) are very rare.

Do germ cell tumors run in families?

Familial testicular germ cell tumors are well known in literature. Only few cases are reported where both brother and sister of the same family suffered from germ cell malignancies.