Is Aromasin a chemotherapy drug?
What Is Aromasin? Aromasin (exemestane) is an antineoplastic (anticancer) agent used to treat breast cancer in postmenopausal women. Aromasin is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox) for 2 to 3 years.
Is Aromasin a hormone therapy?
Aromasin is a kind of endocrine therapy (sometimes called hormone therapy) known as an aromatase inhibitor. Aromasin lowers the level of the hormone estrogen in your body.
Are aromatase inhibitors chemotherapy?
Aromatase inhibitors are extremely potent and important treatments for ER-positive breast cancer. Just as most chemotherapy regimens reduce the risk of recurrence by 50%, so do these pills.
Is hormone therapy considered chemotherapy?
Many patients think of hormone therapy as being “less potent” than chemotherapy, but it can be just as effective in certain breast and prostate cancers. Hormone therapy is considered a “systemic” therapy, meaning that it travels throughout the body. Surgery and radiation therapy are considered “local” treatments.
How long should I stay on Aromasin?
Official Answer. Most women take Aromasin for two to three years. Doctors may recommend some women take it for longer. Aromasin is usually given after two to three years of treatment with tamoxifen, for a total of five years of continuous hormonal treatment.
How fast does Aromasin lower estrogen?
After a single dose of exemestane 25 mg, the maximal suppression of circulating estrogens occurred 2 to 3 days after dosing and persisted for 4 to 5 days.
How long should you stay on exemestane?
This will depend on your individual circumstances, but exemestane is usually taken for five to ten years. Some people start taking exemestane after a few years of taking the hormone therapy drug tamoxifen.
What are the long term side effects of exemestane?
Side effects of exemestane (Aromasin)
- aching or pain in the joints and muscles.
- menopausal symptoms.
- low mood and depression.
- difficulty sleeping.
- fatigue (extreme tiredness)
- osteoporosis (thinning of the bone)
Why aromatase inhibitor is bad for you?
Aromatase inhibitors tend to cause fewer serious side effects than tamoxifen, such as blood clots, stroke, and endometrial cancer. But aromatase inhibitors can cause more heart problems, more bone loss (osteoporosis), and more broken bones than tamoxifen, at least for the first few years of treatment.
Which aromatase inhibitor is best with least side effects?
Anastrozole, exemestane and letrozole are equally effective and have similar side effects [92,106-109]. However, you may tolerate one drug better than another. For a summary of research studies on aromatase inhibitors and early breast cancer, visit the Breast Cancer Research Studies section.
Does Chemo reduce estrogen?
Chemotherapy drugs: Some chemo drugs can damage the ovaries of pre-menopausal women so they no longer make estrogen.
What is the success rate of hormone therapy?
The 6-year survival rate for HRT users was 92% compared with 80% for nonusers (P = . 05) (Figure 2). Figure 3 shows survival curves for patients with tumors detected by palpation. The 6-year survival rate was 79% for HRT users compared with 76% for nonusers (P = .
Why is hormone therapy recommended?
Estrogen therapy can help decrease your risk of certain health conditions, including osteoporosis, heart disease, stroke, dementia and mood changes.