Is sebaceous carcinoma slow-growing?
Sebaceous carcinoma of the eyelid is a very rare slow-growing tumor and is considered an aggressive eyelid neoplasm. It can reach mortality rate of about 6%. Diagnosis is often delayed because of its ability to masquerade as other periocular lesions, both clinically and histologically.
How aggressive is sebaceous carcinoma?
Sebaceous carcinoma is a rare and aggressive malignant cutaneous cancer that arises from the sebaceous gland epithelium. This type of cancer typically presents in the periocular area and is rarely expressed in the extraocular space. The estimated overall incidence rate is one to two per million people per year.
Where does sebaceous carcinoma spread?
As the carcinoma grows it may spread onto the conjunctiva, where it can be mistaken for keratoconjunctivitis or blepharoconjunctivitis. In advanced cases, the spread of the lesion may lead to both upper and lower lid lesions and cause loss of eyelashes (madarosis), ulceration, and distorted vision.
Is sebaceous carcinoma fatal?
Sebaceous carcinoma is a highly aggressive, potentially lethal tumour arising from the sebaceous glands in the skin. It accounts for 3.2 % of all malignant skin tumours. An advanced case of sebaceous carcinoma with distant metastasis is very rare as most of them present in the periocular area and are easily visible.
What does sebaceous gland carcinoma look like?
Sebaceous carcinoma most often affects the eyelids. Sebaceous carcinoma may begin as a painless lump or thickening of skin on the eyelid. As it grows, the cancer may bleed or ooze. Sebaceous carcinoma that occurs on other parts of the body usually appears as a yellowish lump that may bleed.
How common is sebaceous cell carcinoma?
It represents 1–5.5% of eyelid malignancies and is considered to be the third most common eyelid malignancy after basal cell and squamous cell carcinomas, although few reports placed this tumor as second most common after basal cell carcinoma.
Can sebaceous carcinoma be cured?
Sebaceous Carcinoma Treatments
Most sebaceous carcinomas can be treated with surgery. Treatment options may include: Mohs surgery, a highly specialized technique that removes the cancerous tissue while preserving surrounding healthy tissue. Excision or surgical removal of the tumor and some surrounding tissue.
Is sebaceous carcinoma painful?
Sebaceous carcinomas that develop on an eyelid often cause a slow-growing lump to form. It may appear yellow or firm and is often painless.
Is sebaceous adenoma malignant?
The diagnosis of sebaceous adenoma is predominantly based on the characteristic pathologic features. Sebaceous adenoma is a rare, benign tumor of sebaceous glands.
What are the signs and symptoms of sebaceous gland carcinoma?
Sebaceous carcinoma: Signs and symptoms
- Slowly growing, often yellowish lump on the eyelid that feels firm, deep, and painless.
- Thickening of an eyelid, where lid meets lash.
- Yellow or reddish crust on eyelid, where lid meets lash.
- Growth on eyelid that looks like a pimple.
- Growth on eyelid that bleeds.
Can a sebaceous cyst become cancerous?
Sebaceous cysts are common and harmless but, rarely, a sebaceous cyst can become malignant (cancerous). A sebaceous cyst is possibly cancerous if it has any of these characteristics: A sign of infection such as pain, redness or pus drainage. A fast rate of growth after being removed.
Can sebaceous carcinoma metastasis?
Sebaceous gland carcinoma (SGC) of the eyelid is an aggressive malignant eyelid tumor, and it can metastasize to the regional lymph nodes and distant organs.