What level of CEA indicates cancer?
Elevated levels of CEA occur when the CEA is higher than 3 ng/mL. These levels are considered abnormal. People with many types of cancers can have levels that are higher than 3 ng/mL. If you have values that are that high, it doesn’t mean you have cancer.
Does CEA detect all cancers?
High CEA levels may also be a sign of some noncancerous conditions, such as cirrhosis, noncancerous breast disease, and emphysema. A CEA test can’t tell you what kind of cancer you have, or even whether you have cancer. So the test is not used for cancer screening or diagnosis.
How accurate is a CEA blood test?
Sensitivity of CEA ranged from 17.4 % to 100 %, specificity ranged from 66.1 % to 98.4 %, positive predictive value ranged from 45.8 % to 95.2% and negative predictive value ranged from 74.5 % to 100 %.
Is CEA a reliable tumor marker?
Doctors don’t use the CEA test to make a first-time diagnosis of cancer. This test isn’t an accurate way to screen for it because many other diseases can cause the levels of this protein to rise. And some people with cancer don’t have high CEA levels.
What can cause a rise in CEA?
Both benign (harmless) and malignant (cancerous) conditions can increase the CEA level. The most frequent cancer which causes an increased CEA is cancer of the colon and rectum. Others include cancers of the pancreas, stomach, breast, lung, and medullary carcinoma of the thyroid and ovarian cancer.
What is a good CEA level?
The normal range is 0 to 2.5 ng/mL (0 to 2.5 µg/L). In smokers, slightly higher values may be considered normal (0 to 5 ng/mL, or 0 to 5 µg/L).
What does a CEA level of 8 mean?
It is concluded that a rise in CEA to greater than 8 ng/ml indicates with high degree of certainty relapse or disease progression in colorectal cancer patients. CEA is not a reliable indicator of clinical response to chemotherapy, and an increase in the CEA level is of little prognostic value concerning survival.
What does a CEA blood test tell you?
The carcinoembryonic antigen (CEA) test measures the level of CEA in the blood. CEA is a protein normally found in the tissue of a developing baby in the womb. The blood level of this protein disappears or becomes very low after birth. In adults, an abnormal level of CEA may be a sign of cancer.
Can inflammation cause CEA to rise?
Oxaliplatin has been shown to cause an inflammatory response which appears to be one of the mechanisms of toxicity and high CEA levels have been correlated with increased inflammation.
Can stress increase CEA levels?
Our findings clearly indicated that immobilization stress results in enhanced serum CEA level whether the stress is acute or chronic. Consistent with our finding, there are reports suggesting that stress can increase tumor growth and tumor marker expression [26, 27].
What is a normal CA 125 level?
The normal value is less than 46 U/mL. If your CA 125 level is higher than normal, you may have a benign condition, or the test result could mean that you have ovarian, endometrial, peritoneal or fallopian tube cancer. Your doctor may recommend other tests and procedures to determine your diagnosis.