Can a spindle cell tumor be benign?
Spindle cell tumours can be benign (suffix -oma) or malignant (suffix -sarcoma), and will arise from these different cell lines.
Is spindle cell cancer rare?
Primary spindle cell sarcoma (SCS) is an extremely rare entity and one of the least reported tumor2. It is a type of connective tissue tumor and generally begins in layers of connective tissue such as that under the skin, between muscles, and surrounding organs.
Is spindle cell lesions cancer?
Most SpCC are overtly malignant, and the differential diagnosis then includes a number of different malignant spindle cell neoplasms. However, there are several benign or even non-neoplastic lesions that can sometimes be difficult to discern from SpCC.
Is spindle cell carcinoma serious?
Spindle cell carcinoma (SCC) is a rare pulmonary malignancy, accounting for only 0.2%–0.3% of all lung cancers. Therefore, the prognosis and treatment of pulmonary SCC is unclear. There are only 13 reported cases in literature, only three of which had a survival of more than 11 months.
What is the survival rate for spindle cell sarcoma?
The relative 5-year survival rates were 84% for those aged 20 to 49 years and 48% for those 50 to 69 years. Those older than 70 years had a 2-year relative survival rate of only 30%.
How are spindle cell tumors treated?
The usual treatment for spindle cell sarcoma is surgery to remove the tumour. Chemotherapy can be used in certain situations and we will discuss this with you we feel this is a suitable option.
Can spindle cell sarcoma be cured?
A sarcoma is considered stage IV when it has spread to distant parts of the body. Stage IV sarcomas are rarely curable. But some patients may be cured if the main (primary) tumor and all of the areas of cancer spread (metastases) can be removed by surgery. The best success rate is when it has spread only to the lungs.
How long can you live with Stage 4 sarcoma?
The 5-year survival rate for people with locally advanced sarcoma is 56%. About 15% of sarcomas are found in a metastatic stage. The 5-year survival rate for people with metastatic sarcoma is 15%.
How aggressive is spindle cell carcinoma?
Spindle cell carcinoma (SpCC) is an uncommon aggressive biphasic malignancy that has the propensity to manifest itself in the upper aerodigestive tract, including the oral mucosa.
What is a low-grade spindle cell lesion?
Low-grade tumors, locally aggressive
13A), composed of spindle cells with the features of both fibroblasts and myofibroblasts Characteristically the neoplastic cells, often aligned parallel, are arranged in long and sweeping fascicles set in a prominent fibrous to focally myxoid stroma (Fig. 13B,C). Mitoses are rare.
Is spindle cell carcinoma a melanoma?
Spindle cell melanoma (SCM) is a rare subtype of malignant melanoma composed of spindled neoplastic cells arranged in sheets and fascicles (1). The diagnosis of SCM is challenging, as SCM may occur anywhere on the body and frequently mimics amelanotic lesions, including scarring and inflammation (2–4).