How does carboplatin work in the body?
It may be used by itself or combined with other chemotherapy drugs. How does the medicine work? Carboplatin binds to your body’s DNA (the machinery or “brain” that runs each cell) causing damage that prevents the DNA from replicating, which prevents the cell itself from reproducing.
Can carboplatin cure cancer?
What is carboplatin? Carboplatin is used to treat ovarian and lung cancer. It may sometimes be used to treat other cancers.
How does carboplatin help cancer?
Carboplatin is used to treat various types of cancer. It is a chemotherapy drug that contains platinum. It is used to slow or stop cancer cell growth.
How quickly does carboplatin work?
Each dose, or cycle, of carboplatin takes 15 minutes to an hour. It may take longer if you are having carboplatin with other drugs. You’ll usually have one cycle of carboplatin every 21–28 days. The total number of cycles will depend on your particular situation.
What is the success rate of carboplatin?
The 5-year overall survival rates were 66% in cisplatin/vinorelbine group, 55% in carboplatin/vinorelbine group and 70% in cisplatin/vinorelbine/carboplatin/vinorelbine group ( p = 0, 95).
How many cycles of carboplatin can you have?
When you have carboplatin
You might have carboplatin every 3 to 4 weeks. Each 3 or 4 week period is a cycle of treatment. You might have between 4 to 6 cycles.
Does carboplatin affect the heart?
Cardiovascular events. Although infrequent, heart failure, blood clots and strokes have been reported with Carboplatin use. Less than 1% were life-threatening. Allergic reaction may occur.
Does carboplatin cause weight gain?
Although there has not been a systematic analysis to date, there is some evidence that carboplatin combined with paclitaxel can cause weight gain in ovarian cancer patients. Therefore, there may be potential risk-factors related to survival related to either high BMI or weight loss.
Can carboplatin cause heart damage?
Chemotherapy drugs that can cause heart damage include: anthracycline drugs such as doxorubicin (Adriamycin), daunorubicin (Cerubidine, daunomycin) and epirubicin (Pharmorubicin) cisplatin. carboplatin (Paraplatin, Paraplatin AQ)
Can carboplatin shrink tumors?
Chemotherapy drugs, such as docetaxel, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high-energy x-rays to kill tumor cells and shrink tumors.
Does carboplatin cause kidney damage?
Renal failure secondary to carboplatin therapy is due to acute tubular necrosis and is usually reversible. However, acute renal failure with rapid progression to end-stage renal disease is an exceedingly rare complication of carboplatin therapy.
How does carboplatin affect the kidneys?
Carboplatin is considered less nephrotoxic but can still cause tubular injury and interstitial nephritis in patients who have been previously treated with cisplatin. The affected individuals usually have nonoliguric renal failure with a urine output of more than a liter per day.
Can carboplatin cause stroke?
Kuan et al (2014) reported an elevated relative risk (RR) of stroke in patients with ovarian cancer that were treated with cisplatin-based or carboplatin-based chemotherapy agents, as opposed to non-platinum-based regimens (87). Stroke-like events and stroke have been reported in MTX treatment (4,88).
How long does nausea last after carboplatin?
Delayed nausea and vomiting usually starts more than 24 hours after treatment and can last up to a few days after treatment ends. It’s more likely with certain types of chemo or other drug to treat cancer. Ask your doctor if the treatment you’re getting is known to cause delayed nausea and vomiting.
What is the cost of carboplatin?
The cost for carboplatin intravenous solution (10 mg/mL) is around $14 for a supply of 5 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.