Can you have liver cancer with normal AFP?

How accurate is AFP test for liver cancer?

AFP had high overall accuracy, with a c-statistic of 0.87 (95%CI 0.85 – 0.89).

Can you have liver cancer with normal blood work?

Hepatocellular carcinoma (HCC or liver cancer) cannot be diagnosed by routine blood tests. There is only one specific blood test which can be used towards a diagnosis of HCC. This test specifically measures for the levels of the protein alfa-fetoprotein in serum (AFP).

What level of AFP indicates liver cancer?

An AFP level between 10 ng/mL to 20 ng/mL is normal for adults. An extremely high level of AFP in your blood—greater than 400 ng/mL—could be a sign of liver tumors.

Can liver cancer be detected by a blood test?

Liver biopsy

Tests and procedures used to diagnose liver cancer include: Blood tests. Blood tests may reveal liver function abnormalities. Imaging tests.

What happens if an AFP test is positive?

What does it mean if my AFP PLUS test result is screen positive? A positive AFP PLUS test means that you are in a higher likelihood group for having a baby with a neural tube defect or a chromosome abnormality. However, it does not prove by itself that there is anything wrong with the pregnancy.

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What is an abnormal AFP result?

What do the results mean? If your results show higher than normal AFP levels, it may mean your baby has a neural tube defect such as spina bifida, a condition in which the bones of the spine don’t close around the spinal cord, or anencephaly, a condition in which the brain does not develop properly.

Can you see liver cancer on ultrasound?

Ultrasound. Ultrasound is often the first test used to look at the liver. It uses sound waves to create an image on a computer screen. This test can show tumors growing in the liver, which then can be tested for cancer, if needed.

Are white blood cells elevated with liver cancer?

A platelet count can detect liver cancer in its early stages. A white cell count below the normal range can be a sign of an enlarged spleen (splenomegaly) and/or an increase in the blood pressure within the liver’s blood vessels (portal hypertension).

What blood tests are abnormal with liver cancer?

Alpha fetoprotein/serum tumor marker test

An increased level of alpha fetoprotein (AFP) in the blood may be a sign of liver cancer. Other cancers and certain noncancerous conditions, including cirrhosis and hepatitis, may also increase AFP levels. Sometimes the AFP level is normal even when there is liver cancer.

What is the tumor marker for liver cancer?

Alpha-fetoprotein (AFP) is used as a tumor marker to help detect and diagnose cancers of the liver, testicles, and ovaries.

Does high afp always mean cancer?

High levels of AFP can be a sign of liver cancer or cancer of the ovaries or testicles, as well as noncancerous liver diseases such as cirrhosis and hepatitis. High AFP levels don’t always mean cancer, and normal levels don’t always rule out cancer.

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Can liver cancer cured?

Any liver cancer is difficult to cure. Primary liver cancer is rarely detectable early, when it is most treatable. Secondary or metastatic liver cancer is hard to treat because it has already spread. The liver’s complex network of blood vessels and bile ducts makes surgery difficult.