Is ER positive good or bad?
About 70 percent of breast cancer patients have positive ER/PR hormone status. While being ER/PR-positive sounds bad, there’s actually a benefit.
What happens if ER PR is positive?
If breast cancer cells have estrogen receptors, the cancer is called ER-positive breast cancer. If breast cancer cells have progesterone receptors, the cancer is called PR-positive breast cancer. If the cells do not have either of these 2 receptors, the cancer is called ER/PR-negative.
What does ER positive mean in breast cancer?
Hormone status of breast cancers includes: Estrogen receptor (ER) positive. The cells of this type of breast cancer have receptors that allow them to use the hormone estrogen to grow. Treatment with anti-estrogen hormone (endocrine) therapy can block the growth of the cancer cells.
How fast does estrogen positive breast cancer grow?
It was found that growth varied significantly based on the estrogen receptor status of the breast tumors. During an average interval of 57 days, 36 percent of tumors did not change in size, while 64 percent grew. Of those tumors that increased in size, the average gain in volume was 34.5 percent.
Is it better to be hormone receptor-positive or negative?
Hormone receptor-positive cancers tend to grow more slowly than those that are hormone receptor-negative. Women with hormone receptor-positive cancers tend to have a better outlook in the short-term, but these cancers can sometimes come back many years after treatment.
Does ER PR positive need chemo?
Most instances of estrogen receptor (ER)-positive, HER2-negative, node-negative breast cancer <1 cm (T1b), and all cancers ≤0.5 cm (T1a), have a good prognosis with endocrine therapy alone, and do not typically require adjuvant chemotherapy.
Can you be ER-positive and PR negative?
Estrogen receptor status and progesterone receptor status
Breast cancers that are ER-positive tend to be PR-positive. And, cancers that are ER-negative tend to be PR-negative.
What happens if the ER PR is negative?
This means the cancer cells don’t grow in response to hormones. Hormone receptor-negative breast cancer accounts for about 25 to 30 percent of breast cancers. It tends to grow more quickly than hormone receptor-positive breast cancer and is more common in premenopausal women.
Which type of breast cancer has the best prognosis?
Pure mucinous ductal carcinoma carries a better prognosis than more common types of IDCs. Papillary Carcinoma – This is a very good prognosis breast cancer that primarily occur in women over the age of 60.
Is ER positive breast cancer hereditary?
HER2-positive breast cancer is not inherited. Instead, it’s considered a somatic genetic mutation. This type of mutation occurs after conception. Having a close relative with HER2-positive breast cancer does not increase your risk for breast cancer or HER2-positive breast cancer.
Is estrogen positive breast cancer slow growing?
Estrogen receptor/progesterone receptor (ER/PR) positive breast cancers tend to grow more slowly than ER/PR negative cancers, and are more likely to respond to hormone therapy. Approximately two-thirds of breast cancers are ER and/or PR positive.