Best answer: How does liquid based cytology work?

What does liquid-based cytology test for?

A type of Pap test. A Pap test is a procedure in which cells are scraped from the cervix for examination under a microscope. It is used to detect cancer or changes that may lead to cancer.

Why is liquid-based cytology better?

Liquid-based cytology (LBC) has advantages of fewer unsatisfactory smears, faster and more efficient method, more accurate interpretation, less obscuring materials such as blood, mucous, inflammatory cells in smears and the use of residual cell suspension for testing human papillomavirus (HPV) DNA and …

Is liquid-based cytology painful?

Although it is recognised that some women experience pain or bleeding during a cervical cytology test, few studies have quantified physical after-effects of these tests.

What liquid is used in liquid-based cytology?

Turbitec® (Labonord SAS, Templemars, France) is a centrifuge method of liquid-based cytology using an alcoholic fixative fluid, Easyfix® (Labonord). It is now well accepted that the association of liquid-based cytology and human papillomavirus test is indissociable of cervical screening.

Why is the liquid-based Pap test is preferred?

Liquid-based Pap smears improve the diagnostic sensitivity of cervical cytology screening. They have the additional benefit of enabling easy testing for human papillomavirus (HPV). Thin Prep and SurePath are 2 methods currently approved by the FDA.

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Is LBC test painful?

The test may be a little uncomfortable, but it should not be painful. However, if at any point during the examination you feel uncomfortable or in pain, you should inform the doctor or nurse straight away, and you have the right to ask for the test to stop.

How do you take liquid-based cytology?

Liquid-based cytology (LBC) is a new method of preparing cervical samples for cytological examination. Unlike the conventional ‘smear’ preparation, it involves making a suspension of cells from the sample and this is used to produce a thin layer of cells on a slide.

Why do you get Pap smears?

The Pap test (or Pap smear) looks for precancers, cell changes on the cervix that might become cervical cancer if they are not treated appropriately. The HPV test looks for the virus (human papillomavirus) that can cause these cell changes.

What is the difference between conventional and liquid-based Pap smear?

Background: Liquid-based cervical cytology was developed to improve the diagnostic reliability of Papanicolaou (Pap) smears. Conventional Pap smears can have false-negative and false-positive results because of inadequate sampling and slide preparation, and errors in laboratory detection and interpretation.

What is exfoliative cytology?

Exfoliative cytology is a non‐invasive test that uses the Tzanck smear technique to identify disease by examining the structure of cells obtained from scraped samples.

How sensitive is pap smear?

Pap smear had a sensitivity of 55.4 percent and the HPV test had a sensitivity of 94.6 percent. Pap smear had a specificity of 96.8 percent compared with 94.1 percent for the HPV test. The negative predictive value of both tests was higher than 99 percent.

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